PDHK

PDHK Products

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Catalog No. Product Name Information Product Use Citations Product Validations
S4299 Dicoumarol Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Acta Pharmacol Sin, 2023, 1-13.
Anal Chem, 2023, 95(13):5661-5670
Toxicol Lett, 2023, 378:39-50
S7517 AZD7545 AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.
bioRxiv, 2023, 10.1101/2023.04.03.535431
bioRxiv, 2023, 2023.04.03.535431
Bone Res, 2022, 10(1):2
S4299 Dicoumarol Dicoumarol is a competitive NADPH quinone oxidoreductase (NQO1) inhibitor,and used as an anticoagulant by interfering with the metabolism of vitamin K.
Acta Pharmacol Sin, 2023, 1-13.
Anal Chem, 2023, 95(13):5661-5670
Toxicol Lett, 2023, 378:39-50
S7517 AZD7545 AZD7545 is a potent PDHK inhibitor with IC50 of 36.8 nM and 6.4 nM for PDHK1 and PDHK2, respectively. It failed to inhibit PDHK4 at higher concentrations(>10 nM), AZD7545 stimulates PDHK4 activity.
bioRxiv, 2023, 10.1101/2023.04.03.535431
bioRxiv, 2023, 2023.04.03.535431
Bone Res, 2022, 10(1):2

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Tags: PDHK inhibitor|PDHK agonist|PDHK activator|PDHK inducer|PDHK antagonist|PDHK signaling pathway|PDHK assay kit