Estrogen/progestogen Receptor Chemicals

Cat.No.	Product Name	Information	Product Use Citations
S2281	Chrysin	Chrysin (NSC 407436) is a naturally occurring flavone chemically extracted from the blue passion flower (Passiflora caerulea).	Microb Pathog, 2025, 208:107957 Cell Metab, 2022, 34(2):299-316.e6 Cell Metabolism, 2022, 299-316.e6
S1377	Drospirenone	Drospirenone (ZK 3059) is a synthetic progestin that is an analog to spironolactone.	Acta Pharmaceutica Sinica B, 2023, 662-677 Acta Pharm Sin B, 2023, 13(2):662-677 Nature Cancer, 2020, 235-248
S1665	Estrone	Estrone is an estrogenic hormone.	Communications Medicine, 2025, 420 Mol Cell, 2019, 75(6):1103-1116.e9
S5236	β-Estradiol 17-Acetate	β-Estradiol 17-Acetate is a metabolite of estradiol which is an estrogen steroid hormone and the major female sex hormone.	Proceedings of EuroResidue IX: Conference on Residues of Veterinary Drugs in Food, 2022, 45 Cell Death & Disease, 2019, 775 Cell Death Dis, 2019, 10(10):775
S1251	Dienogest	Dienogest (STS 557) is an orally active synthetic progesterone, used for contraception and the treatment of endometriosis.
S1376	Gestodene	Gestodene (SH B 331,WL 70) is a progestogen hormonal contraceptive.
E0527	Norgestimate	Norgestimate, a synthetic progesterone analog, is an orally active progestin with highly selective progestational activity and minimal androgenicity.
S0712	Endoxifen E-isomer	Endoxifen E-isomer (E-Endoxifen), an E-isomer of Endoxifen and impurity in Endoxifen Z-isomer drug substance, exhibits antiestrogenic effects.
E0937	Segesterone acetate	Segesterone acetate (Nestoron, ST-1435) is a synthetic progestin that binds to the progesterone receptor with EC50 of 50.3 nM.
S3818	Tectoridin	Tectoridin (Shekanin), an isoflavone isolated from flowers of Pueraria thunbergiana, has several pharmacological effects including anti-cancer, anti-inflammatory, antioxidant, and hepatoprotectivy.
E0532	Menotropin	Menotropin (Human Menopausal Gonadotrophin) is a hormonally active medication for the treatment of fertility disturbances, which are extracted from the urine of postmenopausal women.
E7063	Endoxifen (Z-isomer)	Endoxifen Z-isomer is the most important Tamoxifen metabolite, inducing an anti-estrogenic effect in breast cancer cells expressing ERα. Endoxifen Z-isomer inhibits hERG. This effect is concentration-dependent, with an IC50 value of 1.6 μM.
S9862	Vepdegestrant (ARV-471)	Vepdegestrant (ARV471) is an orally bioavailable estrogen receptor-targeting (ER-targeting) PROTAC for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer.
S5785	Norethindrone acetate	Norethindrone acetate (19-Norethindrone acetate, NA) is a common synthetic hormone used in oral contraceptives. This compound is a well-tolerated, effective option to manage pain and bleeding for all stages of endometriosis.
S5219	Allylestrenol	Allylestrenol is an orally active progestagen of the 19-nortestosterone series resembling progesterone.
E7105	Coumestrol	Coumestrol, a phytoestrogen present in soybean products, exhibits cytotoxicity via copper-targeted ROS-mediated p53-dependent mechanism in cancer cells. It also suppresses proliferation of ES2 cells with an IC50 of 50 μM.
E4947	Estrone sulfate sodium	Estrone sulfate (Estrone 3-sulfate sodium salt, Premarin), an inactive form of estrogen, serves as a major circulating estrogen in the plasma. It is converted into the active form, estrone (E1), through the action of steroid sulfatase (STS. Estrone sulfate is commonly used in breast cancer research.
S1238	Tamoxifen	Tamoxifen is an orally active, selective estrogen receptor modulator (SERM) which exhibits both estrogenic agonist and antagonist effects. It blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.	Cell Discov, 2025, 11(1):89 Nat Genet, 2025, 57(9):2192-2202 Cell Metab, 2025, 37(8):1715-1731.e11
S3879	Kaempferide	Kaempferide (4'-Methylkaempferol, 4'-O-Methylkaempferol, Kaempferol 4'-methyl ether), a natural compound derived from the roots of kaempferia galanga, has a variety of effects including anti-carcinogenic, anti-inflammatory, anti-oxidant, anti-bacterial and anti-viral properties.