Research Area
Product Type
United States ( Change Country )
BIBR 953(Dabigatran, Pradaxa) Chemical Structure
NXY-059 (Cerovive)
NXY-059 (Cerovive) is the disulfonyl derivative of the neuroprotective spin trap phenylbutynitrone or "PBN".
PTC124 (Ataluren)
PTC124 also known as Ataluren is CFTR-G542X nonsense allele inhibitor.
STF-62247
Targeting VHL-deficient RCC cells, in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 μM).
BTZ043 racemate
BTZ043 racemate is a decaprenylphosphoryl-b-D-ribose 2’-epimerase inhibitor with MIC of 2.3 and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
Odanacatib (MK 0822)
cathepsin K inhibitor with an IC50 of 0.2nM.
L-163191 (MK-0667)
A potent, orally active growth hormone (GH) secretagogue.
[Ala92]-p16 (84-103)
[Ala92]-p16 (84-103) is a CDK inhibitor with IC50 of 1.5μM for cyclin-dependent kinase-4 (cdk4)/cyclin D1
Bax inhibitor peptide,negative control
Bax inhibitor peptide,negative control is a negative control peptide for the Bax inhibitor peptides V5 and P5.
JIP-1(153-163)
JNK and p38 MAPK inhibitor
pp60 c-src (521-533)(phosphorylated)
SRC kinase inhibitor
Biological Activity
BIBR 953(Dabigatran) is a reversible, competitive, direct thrombin inhibitor. It has been shown to be an effective antithrombotic agent in animal models and to be efficacious and safe in the prevention of deep vein thrombosis in patients undergoing elective total hip or knee replacement. [1] Dabigatran etexilate (BIBR 1048 MS, the oral prodrug of dabigatran) is currently in Phase III development for primary prevention of venous thromboembolism (VTE) in patients undergoing major orthopedic surgery, acute VTE treatment, and VTE secondary prevention, as well as stroke prevention in patients with. [1,2]
Product Information
| Molecular Weight (WM): | 471.51 |
|---|---|
| Formula: | C25H25N7O3 |
| CAS No.: | 211914-51-1 |
| Synonyms: |
N/A
|
| Dissolve in (25°C): | DMSO <1mg/mL |
| Water <1mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
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