Home » Products » PLK

Polo-like kinase

Cat.No. Product Name Feedback Added
S1109

BI 2536

Aug 2009
BI 2536 is a Plk1 inhibitor with an IC50 of 0.83 nM.
S2235

BI 6727 (Volasertib)

Apr 2011
BI 6727 is a highly potent Polo-like kinase inhibitor with an IC50 of 0 .87 nM.
S2193

GSK461364

Jan 2011
GSK 461364 is a potent small molecule Polo-like kinase 1 (PLK1) inhibitor with a Ki of 2.2 nM.
S1485

HMN-214

Sep 2010
HMN-214 is a potent PLK1 inhibitor an average IC50 of 0.12 μM.
S1362

ON-01910

Jun 2010
ON-01910 is a non-ATP-competitive small molecule Plk1inhibitor with an IC50 of 9 nM.
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Arnaud AUTRET, Trinity College
"I would like to confirm you that everything is perfectly fine with ABT and Obatoclax we got from your company. We confirmed their activity in vitro. We notably observed their impact in an apoptotic model and results are similar to those which have been published."

Dongfeng Chen, The Rausing Lab
"Your product U0126(Cat.NO S1102) works well in our experiments. I hope I can get more excellent products from your company in future."

Dr. Alexandra Segref, CECAD Cologne,Germay
"I am very satisfied with your product and costumer service. Bortezomib works very well in our assay, it is comparably cheaper than other inhibitors that we tested is more reliable for our assays. We see a great effect by using 10nM concentration."

R.B. Cambridge
"I have used the chemical that I bought from you(Selleck,PTC-124) and it worked well.So we will eventually be ordering more."

Zhenghe John Wang Assistant Professor, Case Western Reserve University
"We have purchased LBH-589, Saha and MS-275 from you and they all worked well."

Jenny Sun
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Yu Wang, Harvard University
"The GDC0449 compound worked very well. The results in my hands are equally good as what's been published. Thanks for this great resource for our research."

Philip Seeman, Toronto University
"Your LY404039 compound was well synthesized, its complicated stereochemical structure confirmed by NMR spectroscopy, and was biologically excellent in acting on brain dopamine receptors."

Dung-Fang Lee
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May 2010
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