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PEG300 Hydrotropic Agents chemical

Name: PEG300
SKU: S6704
Availability: InStock
Rating: 5 (82 reviews)

Cat.No.S6704

PEG300 (Polyethylene glycol 300) is a water-miscible polyether widely used in biochemistry, structural biology, and medicine in addition to pharmaceutical and chemical industries. It serves as a kind of solubilizer, excipient, lubricant, and chemical reagent. This compound helps in the formation of hydrogels in situ upon mixing with silk. These PEG–silk hydrogels are of interest for many biomedical applications, such as anti-fouling and anti-adhesion.

Chemical Structure

Molecular Weight:

Jump to Mechanism of Action Solubility Chemical Information, Storage & Stability

Quality Control

Batch: Purity: 99.99%

99.99

Products Often Used Together with PEG300

Tween 80

Both are co-solvents and can be used together as formulations for animal dosing.

Ferrostatin-1 (Fer-1)

It is used as a vehicle to dissolve ferrostatin-1 in in vivo experiments.

Corn Oil

Both are co-solvents and can be used together as formulations for animal dosing.

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Related Products	CMC-Na SBE-β-CD Tween 80 PEG400 Pluronic F-68 1-Methoxy PMS NOTA Castor oil Corn Oil

Chemical Information, Storage & Stability

Molecular Weight		Formula	(C₂H₄O)nH₂O	Storage (From the date of receipt)	3 years room temperature liquid
CAS No.	25322-68-3	--		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent

Solubility

In vitro
Batch:

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
=	×	×

Dilution Calculator Molecular Weight Calculator

In vivo
Batch:

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg Average weight of animals: g Dosing volume per animal:μL Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO + % + % Tween 80 + % ddH₂O

%DMSO+ %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Mechanism of Action

References	[1] https://www.sciencedirect.com/science/article/abs/pii/S0924203196000744?via%3Dihub [2] https://pubmed.ncbi.nlm.nih.gov/25449912/

Applications

Methods	Biomarkers	Images	PMID
Western blot	P-Akt / Akt / P-mTor / P-S6 / S6 / P-ERK1,2 / ERK1,2 P-FRS2 / FRS2 / P-Akt / Akt / P-S6 / P-ERK1,2 / ERK1,2		23343422

Tech Support

Handling Instructions

Tel: +1-832-582-8158 Ext:3

If you have any other enquiries, please leave a message.

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