Home Others Hydrotropic Agents chemical NOTA For research use only.

NOTA

NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid is a bifunctional chelating agent which acts as the framework to construct PET imaging tools. It is also used for probe design and signal amplification via the multivalent effect and also has potential applications as diagnostic gallium radiopharmaceuticals.

NOTA Chemical Structure

NOTA Chemical Structure

CAS: 56491-86-2

Purity & Quality Control

Batch: S692301 DMSO] 61 mg/mL] false] Water] 50 mg/mL] false] Ethanol] 2 mg/mL] false Purity: >97%
97

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Biological Activity

Description NOTA, i.e. 1,4,7-triazacyclononane-1,4,7-triacetic acid is a bifunctional chelating agent which acts as the framework to construct PET imaging tools. It is also used for probe design and signal amplification via the multivalent effect and also has potential applications as diagnostic gallium radiopharmaceuticals.
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Chemical Information & Solubility

Molecular Weight 303.31 Formula

C12H21N3O6
CAS No. 56491-86-2 SDF --
Smiles OC(=O)CN1CCN(CCN(CC1)CC(O)=O)CC(O)=O
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 61 mg/mL ( (201.11 mM)； Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 50 mg/mL

Ethanol : 2 mg/mL


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In vivo
Batch:

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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