N-Acetyl-5-hydroxytryptamine

Catalog No.S2985 Synonyms: NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin

For research use only.

N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.

N-Acetyl-5-hydroxytryptamine Chemical Structure

CAS No. 1210-83-9

Purity & Quality Control

Choose Selective Trk receptor Inhibitors

Biological Activity

Description

N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.

Targets
TrkB receptor [1]

Protocol (from reference)

Solubility (25°C)

In vitro

Chemical Information

Molecular Weight 218.25
Formula

C12H14N2O2

CAS No. 1210-83-9
Storage 3 years -20°C powder
2 years -80°C in solvent

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Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT05118360 Not yet recruiting Drug: ASC41 2 mg|Drug: ASC41 4 mg|Drug: Placebo Nonalcoholic Steatohepatitis (NASH) Gannex Pharma Co. Ltd. December 1 2022 Phase 2
NCT05211284 Not yet recruiting Drug: Saroglitazar Magnesium 4 mg|Drug: Placebo Nonalcoholic Steatohepatitis Zydus Therapeutics Inc. July 1 2022 Phase 2
NCT05254626 Not yet recruiting Drug: Dapagliflozin 10Mg Tab|Drug: Pioglitazone 30 mg Non-alcoholic Steatohepatitis Cairo University June 2022 Phase 4

(data from https://clinicaltrials.gov, updated on 2022-08-01)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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