N-Acetyl-5-hydroxytryptamine

Synonyms: NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin

N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.

N-Acetyl-5-hydroxytryptamine Chemical Structure

N-Acetyl-5-hydroxytryptamine Chemical Structure

CAS: 1210-83-9

Selleck's N-Acetyl-5-hydroxytryptamine has been cited by 1 publication

Purity & Quality Control

Batch: S298501 DMSO] 43 mg/mL] false] Ethanol] 43 mg/mL] false] Water] Insoluble] false Purity: 99.93%
99.93

N-Acetyl-5-hydroxytryptamine Related Products

Choose Selective Trk receptor Inhibitors

Biological Activity

Description

N-Acetyl-5-hydroxytryptamine (NAS, N-Acetylserotonin, Normelatonin, O-Demethylmelatonin), a precursor of melatonin, is a potent and selective agonist of TrkB receptor.

Targets
TrkB receptor [1]
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NAFLD|PCOS
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Chemical Information & Solubility

Molecular Weight 218.25 Formula

C12H14N2O2

CAS No. 1210-83-9 SDF --
Smiles CC(=O)NCCC1=C[NH]C2=C1C=C(O)C=C2
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 43 mg/mL ( (197.02 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 43 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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