Catalog No.S2407

For research use only.

Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activities.

Curcumol Chemical Structure

CAS No. 4871-97-0

Selleck's Curcumol has been cited by 5 Publications

Purity & Quality Control

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Biological Activity

Description Curcumol is a pure monomer isolated from Rhizoma Curcumaeis with antitumor activities.
JAK [2]
In vitro

Curcumol induced cell death in human lung adenocarcinoma (ASTC-a-1) cells by inducing G(2)/M phase arrest, nuclear fragmentation, phosphatidylserine externalization and a rapid translocation of Bax from cytosol into mitochondria. While, caspases are not involved in Curcumol-induced apoptosis. [1] Curcumol also benefits rheumatoid arthritis treatment through suppressing the fibroblast-like synoviocytes (FLS) proliferation and DNA synthesis. It attenuates PDGF-BB-induced Jak2 phosphorylation and downregulates STAT1 and STAT3 DNA-binding activities. [2]

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 47 mg/mL
(198.85 mM)
Ethanol 47 mg/mL
(198.85 mM)
Water Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 236.35


CAS No. 4871-97-0
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles CC1CCC2C13CC(C(O3)(CC2=C)O)C(C)C

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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