| S7072 |
NMDA (N-Methyl-D-aspartic acid)
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NMDA (N-Methyl-D-aspartic acid) is a specific agonist for the NMDA receptor, mimicking the action of glutamate, the neurotransmitter which normally acts at that receptor. Phase 4.
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Theranostics, 2025, 15(14):6901-6918
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Sci Rep, 2025, 15(1):17364
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J Neurotrauma, 2025, 10.1177/08977151251374286
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| S6266 |
(S)-Glutamic acid
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(S)-Glutamic acid (L-Glutamic acid) is an endogenous, non-selective glutamate receptor agonist.
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Cell Biosci, 2024, 14(1):135
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Cancer Sci, 2022, 113-6:1955-1967
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CHEM ENG J, 2021, 10.1016/j.cej.2021.130083
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| S4721 |
L-Glutamic acid monosodium salt
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L-Glutamic acid monosodium salt is the sodium salt of glutamic acid, found naturally in tomatoes, cheese and other foods. This compound acts as an excitatory transmitter and an agonist at all subtypes of glutamate receptors (metabotropic, kainate, NMDA, and AMPA). It shows a direct activating effect on the release of DA from dopaminergic terminals.
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Heliyon, 2024, 10(1):e23945
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Acta Biomater, 2022, 152:255-272
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| S3624 |
Quinolinic acid
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Quinolinic Acid (pyridine-2,3-dicarboxylic acid, QUIN), a neuroactive metabolite of the kynurenine pathway, is an agonist of N-methyl-D-aspartate (NMDA) receptor.
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| S3070 |
Piracetam
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Piracetam (UCB 6215) is a cyclic derivative of the neurotransmitter gamma-aminobutyric acid (GABA), used in treatment of a wide range of cognitive disorders.
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| S6907 |
Rapastinel (GLYX-13)
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Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targets a glycine site, and it has long-lasting antidepressant effects.
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| S6224 |
(R)-Serine
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(R)-Serine is the R-enantiomer of serine, which is used in the biosynthesis of proteins. This compound acts as obligatory coagonist at the glycine site associated with the N-methyl-D-aspartate subtype of glutamate receptors (NMDAR) and has a cardinal modulatory role in major NMDAR-dependent processes including NMDAR-mediated neurotransmission, neurotoxicity, synaptic plasticity, and cell migration.
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| S5669 |
Isoxsuprine hydrochloride
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Isoxsuprine hydrochloride is a beta-adrenergic agonist with vasodilator activity.
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| S6803 |
1-BCP
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1-BCP (Piperonylic acid piperidide) is a memory-enhancing agent that enhances AMPA-induced currents.
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