Haspin Kinase antagonist | Haspin Kinase inhibitor | Haspin Kinase agonist

Catalog No.	Product Name	Information	Product Use Citations
E1132^New	CHR-6494	CHR-6494 is a potent inhibitor of haspin, with an IC50 of 2 nM, inhibits histone H3T3 phosphorylation, and can be used in the research of cancer.
S2198	SGI-1776 free base	SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. SGI-1776 induces apoptosis and autophagy. Phase 1.	Int J Gynecol Pathol, 2022, 10.1097/PGP.0000000000000882 Cancer Res, 2021, 81(23):6029-6043 Cancer Res, 2021, canres.1023.2021
S3406	LDN-192960	LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 of 10 nM and 48 nM, respectively.	Colloids Surf B Biointerfaces, 2022, 209(Pt 1):112182
E1132^New	CHR-6494	CHR-6494 is a potent inhibitor of haspin, with an IC50 of 2 nM, inhibits histone H3T3 phosphorylation, and can be used in the research of cancer.
S2198	SGI-1776 free base	SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. SGI-1776 induces apoptosis and autophagy. Phase 1.	Int J Gynecol Pathol, 2022, 10.1097/PGP.0000000000000882 Cancer Res, 2021, 81(23):6029-6043 Cancer Res, 2021, canres.1023.2021
S3406	LDN-192960	LDN-192960 (Compd 1) is a potent inhibitor of Haspin and Dual-specificity Tyrosine-regulated Kinase 2 (DYRK2) with IC50 of 10 nM and 48 nM, respectively.	Colloids Surf B Biointerfaces, 2022, 209(Pt 1):112182
E1132^New	CHR-6494	CHR-6494 is a potent inhibitor of haspin, with an IC50 of 2 nM, inhibits histone H3T3 phosphorylation, and can be used in the research of cancer.

Haspin Kinase

Haspin Kinase Products