Drug Metabolite Chemicals

Cat.No.	Product Name	Information
S5148	2-Methylenebutyrolactone	2-Methylenebutyrolactone (Tulipalin A, MBL, α-methylene-γ-butyrolactone), also known as α-methylene-γ-butyrolactone (MBL) (Tulipalin A), belongs to the class of sesquiterpene lactone family and is considered as cyclic analog of most common vinyl monomer methyl methacrylate (MMA).
S5681	Vinburnine	Vinburnine ((-)-Eburnamonine, Vincamone, L-Eburnamonine) is a vasodilator. It is a vinca alkaloid and a metabolite of vincamine.
E4608	4-Hydroperoxy cyclophosphamide	4-Hydroperoxy cyclophosphamide is the active metabolite form of the precursor Cyclophosphamide. 4-Hydroperoxy cyclophosphamide cross-links DNA to induce T cell apoptosis independent of caspase receptor activation, and can activate the mitochondrial death pathway by producing reactive oxygen species (ROS). 4-Hydroperoxy cyclophosphamide can be used in the study of rheumatoid arthritis and autoimmune diseases.
S5672	Hydroxyhexamide	Hydroxyhexamide is a pharmacologically active metabolite of acetohexamide, which is a sulfonylurea hypoglycemic agent.
E4922	Allopurinol riboside	Allopurinol riboside, a metabolite of allopurinol, competitively inhibits the action of purine nucleoside phosphorylase on inosine in vitro with a Ki value of 277 μM. It displays potent activities against parasites.
E7914	Desisobutyryl-ciclesonide	Desisobutyryl-ciclesonide is the active metabolite of ciclesonide. It exhibits potent anti-inflammatory activity by effectively inhibiting allergen-induced T-cell proliferation and interleukin-4 expression in vitro and that may have clinical relevance.
S6014	Isonicotinic acid	Isonicotinic acid (Isoniazid, 4-pyridinecarboxylic acid, p-pyridinecarboxylic acid, 4-Picolinic acid) is a metabolite of isoniazid. It is an isomer of nicotinic acid.
S5826	Monobutyl phthalate	Monobutyl phtalate is a metabolite of di(n-butyl)phthalate. It affects the expressions of EMT-related proteins and enhances the migration and invasion of MLTC-1 cells.
S4448	Imidacloprid-urea	Imidacloprid-urea with a role as a marine xenobiotic metabolite, is the primary imidacloprid soil metabolite, whereas imidacloprid-olefin is the main plant-relevant metabolite and is more toxic to insects than imidacloprid.
S3370	3-Methoxytyramine hydrochloride	3-Methoxytyramine (3-O-methyl Dopamine, 3MT) hydrochloride, a major extracellular metabolite of dopamine, is a neuromodulator that in certain situations may be involved in movement control.
E8060	N-Acetylprocainamide	N-Acetylprocainamide is a class III antiarrhythmic, which blocks K+ channels.
S0320	Cycloguanil hydrochloride	Cycloguanil hydrochloride, an active metabolite of proguanil, acts on malaria schizonts in erythrocytes and hepatocytes.
S5834	p-Coumaric acid ethyl ester	p-Coumaric acid ethyl ester is the ethyl ester of p-Coumaric acid, which is a plant metabolite which exhibits antioxidant and anti-inflammatory properties.
S5840	Palifosfamide	Palifosfamide (ZIO-201, Isophosphamide mustard) is a novel DNA alkylator and the active metabolite of ifosfamide with potential antineoplastic activity.