Home Metabolism Drug Metabolite

Drug Metabolite Agonists

Cat.No. Product Name Information Product Use Citations Product Validations
S6887 Clozapine N-oxide (CNO chemical) CNO (Clozapine N-oxide) is a metabolite of Clozapine (GLXC-06516) and an agonist of human muscarinic designer receptors (Designer Receptors Exclusively Activated by Designer Drugs, DREADDs). Clozapine is a potent dopamine (DA) antagonist and a selective muscarinic M4 receptor agonist.Solutions are unstable and should be fresh-prepared.
Theranostics, 2025, 15(5):1822-1841
STAR Protoc, 2025, 6(1):103542
Theranostics, 2024, 14(7):2881-2896
S6889 Monomethyl Fumarate Monomethyl Fumarate (MMF, Monomethylfumarate, Fumaric acid monomethyl ester, Methyl hydrogen fumarate), the active metabolite of the psoriasis drug Fumaderm, is a potent GPR109A agonist. This compound prevents major dysfunctions associated with neurodegenerative diseases: oxidative stress, mitochondrial dysfunction, apoptosis and autophagy.
Cell Cycle, 2022, 1-11.
Aging (Albany NY), 2021, 13(13):17097-17117
S4207 Clofibric Acid Clofibric acid(Chlorofibrinic acid) is a PPARα agonist and hypolipidemic agent.
Lab Invest, 2023, 103(1):100004
S6601 (±)-Equol (±)-Equol, an isoflavandiol estrogen, is a metabolite of the soy isoflavones, daidzin and daidzein.