Cyclin

Cat.No. Product Name Information Product Use Citations Product Validations
P1267New CIRC-014 CIRC-014 is an orally bioavailable cyclin A/B RxL macrocyclic inhibitor. CIRC-014 displays robust anti-tumor activity in chemo-resistant small cell lung cancer (SCLC) PDX models and induces SAC activation and apoptosis in vivo.