| S7889 |
Xanthohumol
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Xanthohumol, a prenylated chalcone from hop, inhibits COX-1 and COX-2 activity and shows chemopreventive effects. This compound inhibits diacylglycerol acyltransferase 1 (DGAT1) and DGAT2 with both IC50 of 40 μM. It is also a potent antiviral agent against a series of DNA and RNA viruses. This chemical induces growth inhibition and apoptosis in cancer cells. Phase 1.
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Oncotarget, 2025, 16:532-544
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J Cell Sci, 2024, 137(20)jcs262162
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Antiviral Res, 2022, 207:105416
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| S1516 |
Cidofovir
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Cidofovir suppresses virus replication by selective inhibition of viral DNA synthesis.
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Journal of Virology, February 5, 2019, e01806-18
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Antiviral Research, February 2019, 178-185
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Oncol Lett, 2021, 21(4):280
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