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KLF Products

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  • KLF Activator (1)
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Catalog No. Product Name Information Product Use Citations Product Validations
S8196 ML264 ML264 (CID-51003603), a selectively inhibitor of kruppel-like factor 5 (KLF5),potently Inhibits Growth of Colorectal Cancer.
Nat Commun, 2025, 16(1):480
Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9
Genome Instability & Disease, 2023, 4, 21–37
S8900 SR18662 SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.
J Exp Clin Cancer Res, 2023, 42(1):25
S6963 APTO-253

APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4).
Cell Commun Signal, 2023, 21(1):94
S8196 ML264 ML264 (CID-51003603), a selectively inhibitor of kruppel-like factor 5 (KLF5),potently Inhibits Growth of Colorectal Cancer.
Nat Commun, 2025, 16(1):480
Nat Biomed Eng, 2024, 10.1038/s41551-024-01273-9
Genome Instability & Disease, 2023, 4, 21–37
S8900 SR18662 SR18662 is an optimized compund based on ML264 that inhibits Krüppel-like factor 5 (KLF5) with IC50 of 4.4 nM. SR18662 reduces the viability of multiple colorectal cancer cell lines. SR18662 induces apoptosis.
J Exp Clin Cancer Res, 2023, 42(1):25
S6963 APTO-253

APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4).
Cell Commun Signal, 2023, 21(1):94

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