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KLF4 Selective Activators

KLF4
KLF5

Catalog No.	Product Name	Information	Selective / Pan	IC50 / Ki
S6963	APTO-253	APTO-253 (LOR-253, LT-253) inhibits c-Myc expression and selectively induces CDKN1A (p21), promotes G0-G1 cell-cycle arrest, and triggers apoptosis in acute myeloid leukemia (AML) cells. APTO-253 is also an inducer of KLF4 (Krüppel-like factor 4).	Selective