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ATPase Activators

Cat.No. Product Name Information Product Use Citations Product Validations
S6815 CDN1163 CDN1163 is a small molecular allosteric activator of the sarco/endoplasmic reticulum Ca2+-ATPase (SERCA) that improves Ca2+ homeostasis.
Stem Cell Res Ther, 2025, 16(1):208
Cell Rep, 2024, 43(10):114784
J Clin Invest, 2022, 132(8)e149160
E4087 Sodium oleate Sodium oleate (Oleic acid sodium salt) is an abundant monounsaturated fatty acid sodium. It is a Na+/K+ ATPase activator and inhibits cancer cell growth and survival in low metastatic carcinoma cells, such as gastric carcinoma SGC7901 and breast carcinoma MCF-7 cell lines.
J Med Chem, 2025, 68(7):7180-7196
J Cell Mol Med, 2025, 29(7):e70524
Journal of Cellular and Molecular Medicine, 2025, e70524
S9181 Periplocin Periplocin (Periplocoside), extracted from the traditional herbal medicine cortex periplocae, has cardiac and anticancer activity. This compound could significantly boost proliferation, migration and stimulate collagen production in fibroblast L929 cells, which is dependent on activation of Src/ERK and PI3K/Akt pathways mediated by Na/K-ATPase, and thus promoting wound healing.
Journal of Oncology, July 05 2022, 8055004
Cancers, February 28 2023, 1526
Journal of Oncology, 5 July 2022, 8055004
S1238 Tamoxifen Tamoxifen is an orally active, selective estrogen receptor modulator (SERM) which exhibits both estrogenic agonist and antagonist effects. It blocks estrogen action in breast cells and can activate estrogen activity in other cells, such as bone, liver, and uterine cells. Tamoxifen is a potent Hsp90 activator and enhances the Hsp90 molecular chaperone ATPase activity.
Cell Discov, 2025, 11(1):89
Nat Genet, 2025, 57(9):2192-2202
Cell Metab, 2025, 37(8):1715-1731.e11
Verified customer review of Tamoxifen
S2623 Omecamtiv mecarbil (CK-1827452) Omecamtiv mecarbil (CK-1827452) is a specific cardiac myosin activator and a clinical drug for left ventricular systolic heart failure, currently in Phase 2.
Nat Biotechnol, 2025, 10.1038/s41587-025-02725-6
Eur Heart J, 2025, ehaf813
Journal of General Physiology, 2025, e202513762
Verified customer review of Omecamtiv mecarbil (CK-1827452)
S4707 Oleic acid (cis-9-Octadecenoic acid) Oleic acid (Oleate, 9-Octadecenoic Acid, Elaidoic acid) is a fatty acid that occurs naturally in various animal and vegetable fats and oils. It is used commercially in the preparation of oleates and lotions, and as a pharmaceutical solvent. Oleic acid is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.Oleic Acid can be used to induce animal models of Renal Failure.
Life Sci, 2025, 374:123687
Sci Rep, 2025, 15(1):28774
J Ovarian Res, 2025, 18(1):180