Tranexamic Acid

Catalog No.S1875

Tranexamic Acid  Chemical Structure

Molecular Weight(MW): 157.21

Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

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Purity & Quality Control

Biological Activity

Description Tranexamic Acid is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived plasminogen fragments with IC50 of 5 mM.

Protocol

References

Solubility (25°C)

In vitro Water 31 mg/mL (197.18 mM)
DMSO Insoluble
Ethanol Insoluble

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 157.21
Formula

C8H15NO2

CAS No. 1197-18-8
Storage powder
Synonyms N/A

Bio Calculators

Molarity Calculator

Molarity Calculator

Calculate the mass, volume or concentration required for a solution. The Selleck molarity calculator is based on the following equation:

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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*When preparing stock solutions, please always use the batch-specific molecular weight of the product found on the via label and MSDS / COA (available on product pages).

Dilution Calculator

Dilution Calculator

Calculate the dilution required to prepare a stock solution. The Selleck dilution calculator is based on the following equation:

Concentration (start) x Volume (start) = Concentration (final) x Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2 ( Input Output )

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* When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / COA (available online).

The Serial Dilution Calculator Equation

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Definitions of molecular mass, molecular weight, molar mass and molar weight:

Molecular mass (molecular weight) is the mass of one molecule of a substance and is expressed in the unified atomic mass units (u). (1 u is equal to 1/12 the mass of one atom of carbon-12)
Molar mass (molar weight) is the mass of one mole of a substance and is expressed in g/mol.

Molarity Calculator

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Clinical Trial Information

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT02329756 Not yet recruiting Placenta Accreta Baylor College of Medicine July 2017 Phase 3
NCT02840097 Not yet recruiting Brain Injuries|Wounds and Injuries|Hemorrhage University of California, Davis|Pediatric Emergency Care Applied Research Network July 2017 Phase 2
NCT02936661 Not yet recruiting Postpartum Hemorrhage, Cesarean Section Shanghai First Maternity and Infant Hospital April 2017 Phase 4
NCT02972294 Not yet recruiting Hip Fractures Pathologic|Anemia University Hospital, Angers February 2017 Phase 3
NCT02908516 Not yet recruiting Hip Fractures|Blood Loss Yale University February 2017 Phase 4
NCT02867163 Recruiting Venous Thrombosis University of New Mexico January 2017 --

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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Cell Lines Assay Type Concentration Incubation Time Formulation Activity Description PMID