SHP1705

Name: SHP1705
Brand: Selleck Chemicals
SKU: E8299
Rating: 5 (1 reviews)

Synonyms: KRASG12C IN-13

Catalog No.E8299 Purity:≥99%

SHP1705 is a potent and selective activator of Cryptochrome 2 (CRY2). It inhibits BMAL1-CLOCK transcriptional activity and significantly enhances efficacy against glioblastoma stem cells (GSCs) and PDX tumors and can be used in research on GSC biology and survival in glioblastoma (GBM).

SHP1705 Chemical Structure

CAS No. 1817737-04-4

Purity & Quality Control

≥99

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Biological Activity

Description	SHP1705 is a potent and selective activator of Cryptochrome 2 (CRY2). It inhibits BMAL1-CLOCK transcriptional activity and significantly enhances efficacy against glioblastoma stem cells (GSCs) and PDX tumors and can be used in research on GSC biology and survival in glioblastoma (GBM).

References

https://pubmed.ncbi.nlm.nih.gov/40168112/

Chemical Information & Solubility

Molecular Weight		Formula
CAS No.	1817737-04-4	SDF	--
Density	g/mL
Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years-20°Cpowder		1 month-20°Cin solvent

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Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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