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L-Proline

Cat.No.S5629

L-Proline is one of non-essential amino acids and an essential component of collagen that is important for proper functioning of joints and tendons.
L-Proline Chemical Structure

Chemical Structure

Molecular Weight: 115.13

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Quality Control

Batch: S562901 Water]23 mg/mL]false]DMSO]Insoluble]false]]]false Purity: 99.99%
99.99

Solubility

In vitro
Batch:

Water : 23 mg/mL

DMSO : Insoluble
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

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In vivo
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In vivo Formulation Calculator (Clear solution)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight 115.13 Formula

C5H9NO2

 Storage (From the date of receipt) 3 years -20°C powder
CAS No. 147-85-3 -- Storage of Stock Solutions

Synonyms N/A Smiles C1CC(NC1)C(=O)O

Mechanism of Action

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT06340685 Recruiting
Pyruvate Dehydrogenase Complex Deficiency
Jirair Krikor Bedoyan|Ultragenyx Pharmaceutical Inc|University of Pittsburgh
 May 2024 Phase 1
NCT05312736 Recruiting
Gyrate Atrophy|Gyrata of Choroid and Retina; Atrophy|Ornithine-δ-aminotransferase|OAT|Chorioretinal Degeneration
Jaeb Center for Health Research|Conquering Gyrate Atrophy Foundation|Food and Drug Administration (FDA)|Department of Health and Human Services
 November 21 2023 --
NCT05775276 Not yet recruiting
Incidence of Mesh Infection In Hernioplasty
Assiut University
 March 2023 Not Applicable
NCT05270525 Recruiting
COPD
Verona Pharma plc|University of Alabama at Birmingham
 May 27 2022 Phase 2
NCT05319262 Completed
Noise Exposure|Sleep Disturbance|Sleep Hygiene|Metabolic Disturbance|Cognitive Change
Göteborg University|University of Pennsylvania|University of Manitoba
 April 24 2022 Not Applicable

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