Inulin

Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.

Inulin Chemical Structure

Inulin Chemical Structure

CAS: 9005-80-5

Purity & Quality Control

Inulin Related Products

Biological Activity

Description Inulin(Inulin and sodium chloride), a starch found in the tubers and roots of many plants. Since it is hydrolyzable to fructose, it is classified as a fructosan.
In vitro
In vitro Inulin causes (20 g/d and 40 g/d) a significant increase in bifidobacterial counts in feces.[1] Inulin exerts a preferential stimulatory effect on numbers of the health-promoting genus Bifidobacterium, whilst maintaining populations of potential pathogens (Escherichia coli, Clostridium) at relatively low levels. [2] Inulin combined with Bifidobacterium results in more potent inhibition of aberrant crypt foci (ACF) than administration of the two separately, achieving 80% inhibition of small ACF. [3] Inulin is made by a set of linear chains of fructose molecules, with a degree of polymerization (DP) ranging between 3 and 65, it can be fractionated into a slowly fermentable long-chain fraction (DP ranging from 10 to 65, average 25) or in a rapidly fermentable fraction made of oligofructose (DP ranging from 3 to 8, average 4). [4] Long-chain inulin combined with short-chain oligofructose results in larger numbers of caecal, colonic and faecal bacteria of the Clostridium coccoides-Eubacterium rectale cluster than Control in rats, whereas OF alone does not affect this bacterial group in caecum, colon or faeces. [5]
In Vivo
In vivo Inulin results in an increase in caecal wt and beta-glucosidase activity and a decrease in caecal pH were observed in rats given inulin-containing diets (with or without B. longum). [3]
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT05254340 Active not recruiting
Healthy
Indiana University|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
August 1 2021 Not Applicable
NCT03983434 Active not recruiting
IBS - Irritable Bowel Syndrome
Indiana University|National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
August 13 2019 Not Applicable

Chemical Information & Solubility

Molecular Weight Formula

C6nH10n+2O5n+1

CAS No. 9005-80-5 SDF Download Inulin SDF
Smiles OCC1OC(OC2(CO)OC(CO)C(O)C2O)C(O)C(O)C1O
Storage (From the date of receipt)

In vivo
Batch:

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In vivo Formulation Calculator

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Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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