Name: Erythritol
Brand: Selleck Chemicals
SKU: S4224
Availability: InStock
Rating: 5 (1 reviews)

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Quality Control

Batch: S422401 DMSO]24 mg/mL]false]Water]24 mg/mL]false]Ethanol]Insoluble]false Purity: 100.0%

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COA
NMR
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Datasheet

100.0

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Solubility

In vitro
Batch:

DMSO : 24 mg/mL (196.52 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 24 mg/mL

Ethanol : Insoluble

Molarity Calculator

Mass	Concentration	Volume	Molecular Weight
Mass value Mass unit	Concentration value Concentration unit	Volume value Volume unit	Molecular weight (g/mol)

Dilution Calculator Molecular Weight Calculator

In vivo batch selection In vivo Batch:
Homogeneous suspension	CMC-NA	≥5mg/ml	Taking the 1 mL working solution as an example, add 5 mg of this product to 1 ml of CMC-Na solution, mix evenly to obtain a homogeneous suspension with a final concentration of 5 mg/ml.

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

Dosage: mg/kg

Average weight of animals: g

Dosing volume per animal: μL

Number of animals:

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO

%

% Tween 80

% ddH₂O

% DMSO

+

%

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH₂O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Chemical Information, Storage & Stability

Molecular Weight	122.12	Formula	C₄H₁₀O₄	Storage (From the date of receipt)	3 years-20°Cpowder
CAS No.	149-32-6	Download SDF		Storage of Stock Solutions	1 year-80°Cin solvent 1 month-20°Cin solvent
Synonyms	meso-Erythritol			Smiles	C(C(C(CO)O)O)O

Mechanism of Action

In vitro	Erythritol is a four-carbon sugar alcohol (polyol) that has a sweetness 60 to 80% that of sucrose and is intended for use in food principally as a low-calorie sweetener. This compound administered orally is rapidly absorbed from the gastrointestinal tract. It is not systemically metabolized and is rapidly excreted unchanged in the urine.
References	[1] https://pubmed.ncbi.nlm.nih.gov/9862657/

Clinical Trial Information

(data from https://clinicaltrials.gov, updated on 2024-05-22)

NCT Number	Recruitment	Conditions	Sponsor/Collaborators	Start Date	Phases
NCT03986476	Completed	IBS	Örebro University Sweden	March 26 2019	Not Applicable
NCT03624569	Unknown status	Cardiovascular Diseases\|Endotoxemia\|Endothelial Dysfunction\|Postprandial Hyperglycemia\|Gut Health	Ohio State University\|Alliance for Potato Research and Education	August 15 2018	Not Applicable

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Erythritol

Chemical Structure

Molecular Weight: 122.12