Azomycin

Catalog No.S2267

Azomycin is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.

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In DMSO USD 70 In stock
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USD 70 In stock
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Azomycin Chemical Structure

Azomycin Chemical Structure
Molecular Weight: 113.07

Validation & Quality Control

Quality Control & MSDS

Related Compound Libraries

Azomycin is available in the following compound libraries:

Product Information

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Product Description

Biological Activity

Azomycin(2-Nitroimidazole) is an antimicrobial antibiotic produced by a strain of Nocardia mesenterica.It has been reported to be active against aerobic Gram-positive and Gram-negative bacteria. It was found that the antibiotic was also active against a variety of anaerobic bacteria.

Conversion of different model animals based on BSA (Value based on data from FDA Draft Guidelines)

SpeciesBaboonDogMonkeyRabbitGuinea pigRatHamsterMouse
Weight (kg)121031.80.40.150.080.02
Body Surface Area (m2)0.60.50.240.150.050.0250.020.007
Km factor202012128653
Animal A (mg/kg) = Animal B (mg/kg) multiplied by  Animal B Km
Animal A Km

For example, to modify the dose of resveratrol used for a mouse (22.4 mg/kg) to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the Km factor for a mouse and then divide by the Km factor for a rat. This calculation results in a rat equivalent dose for resveratrol of 11.2 mg/kg.

Rat dose (mg/kg) = mouse dose (22.4 mg/kg) ×  mouse Km(3)  = 11.2 mg/kg
rat Km(6)

Clinical Trial Information( data from http://clinicaltrials.gov, updated on 2014-09-13)

NCT Number Recruitment Conditions Sponsor
/Collaborators
Start Date Phases
NCT00588276 Completed Cervical Cancer|HEENT Cancer|Renal Cancer|Uterine Cancer|CERVIX UTERI NOS|RECTUM Memorial Sloan-Kettering Cancer Center|National Cancer Institute (NCI) June 2005 --

Chemical Information

Download Azomycin SDF
Molecular Weight (MW) 113.07
Formula

C3H3N3O2

CAS No. 527-73-1
Storage 3 years -20℃Powder
6 months-80℃in DMSO
Synonyms 2-Nitroimidazole
Solubility (25°C) * In vitro DMSO 23 mg/mL (203 mM)
Water <1 mg/mL (<1 mM)
Ethanol 23 mg/mL (203 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Research Area

Tech Support & FAQs

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Tel: +1-832-582-8158 Ext:3

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