Alprostadil (PGE1)

Synonyms: Prostaglandin-E1, Liprostin

Alprostadil (PGE1) is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.

Alprostadil (PGE1) Chemical Structure

Alprostadil (PGE1) Chemical Structure

CAS: 745-65-3

Selleck's Alprostadil (PGE1) has been cited by 2 publications

Purity & Quality Control

Batch: Purity: 100%
100

Alprostadil (PGE1) Related Products

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Biological Activity

Description Alprostadil (PGE1) is used as a drug in the treatment of erectile dysfunction and has vasodilatory properties. It is a Prostaglandin Analog and Prostaglandin E1 Agonist.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT00610051 Not yet recruiting
Heart Failure
Biopeutics Co. Ltd
October 2023 Phase 3
NCT06037525 Completed
Pain|Catheter Infection
University Hospital Augsburg
January 1 2018 --
NCT01776320 Withdrawn
Erectile Dysfunction
Lawson Health Research Institute
December 2013 Phase 4
NCT02889822 Completed
Cardiovascular Diseases
Guangzhou Yipinhong Pharmaceutical CO.LTD
March 2010 Phase 1

Chemical Information & Solubility

Molecular Weight 354.48 Formula

C20H34O5

CAS No. 745-65-3 SDF Download Alprostadil (PGE1) SDF
Smiles CCCCCC(C=CC1C(CC(=O)C1CCCCCCC(=O)O)O)O
Storage (From the date of receipt)

In vitro
Batch:

DMSO : 71 mg/mL ( (200.29 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : 71 mg/mL

Water : Insoluble


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In vivo
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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

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