TET

Other Epigenetics Related Inhibitors

Histone Methyltransferase BET DNA Methyltransferase p300/CBP Histone Demethylase Histone Acetyltransferase MicroRNA NSD EZH1 RNA Methyltransferase

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S6682	Bobcat339 Hydrochloride	Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.	Psychopharmacology (Berl), September 13, 2025, Online ahead of print Cell Reports, March 26, 2025, 115480 Cell Communication and Signaling, February 2, 2024, 95

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S6682

Bobcat339 Hydrochloride

Bobcat339 is a selective cytosine-based TET enzyme inhibitor with IC50 of 33 μM and 73 μM for TET1 and TET2, respectively. Bobcat339 can reduce DNA 5-hydroxymethylcytosine abundance by inhibiting TET enzyme function in living cells and provide support for its utility as a viable pharmacological probe.

Psychopharmacology (Berl), September 13, 2025, Online ahead of print

Cell Reports, March 26, 2025, 115480

Cell Communication and Signaling, February 2, 2024, 95