Name: Guanosine 5'-triphosphate trisodium salt
Brand: Selleck Chemicals
SKU: S3084
Rating: 5 (1 reviews)

Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt is an enhancer of myogenic cell differentiation in a murine cells. Guanosine 5'-triphosphate trisodium salt up-regulates miRNA (specifically miR133a and miR133b) and myogenic regulator factor and induces human myogenic precursor cells to release exosomes stuffed with guanosine based molecules (mainly guanosine) in the extracellular milieu.

Guanosine 5'-triphosphate trisodium salt Chemical Structure

CAS: 36051-31-7

Purity & Quality Control

Batch: S308401 Water] 100 mg/mL] false] DMSO] Insoluble] false] Ethanol] Insoluble] false Purity: 98.25%

98.25

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Biological Activity

Description

Guanosine 5'-triphosphate (5'-GTP, Guanosine triphosphate, H4GTP) trisodium salt is an enhancer of myogenic cell differentiation in a murine cells. Guanosine 5'-triphosphate trisodium salt up-regulates miRNA (specifically miR133a and miR133b) and myogenic regulator factor and induces human myogenic precursor cells to release exosomes stuffed with guanosine based molecules (mainly guanosine) in the extracellular milieu.

References

[1] Tiziana Pietrangelo, et al. Front Pharmacol. 2018 Mar 16;9:152.

Chemical Information & Solubility

Molecular Weight	589.13	Formula	C₁₀H₁₃N₅Na₃O₁₄P₃
CAS No.	36051-31-7	SDF	--
Smiles	[Na+].[Na+].[Na+].NC1=NC2=C(N=C[N]2C3OC(CO[P](O)(=O)O[P]([O-])(=O)O[P]([O-])([O-])=O)C(O)C3O)C(=O)N1
Storage (From the date of receipt)	3 years -20°C powder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
Storage (From the date of receipt)	3 years -20°C powder		1 month-20°Cin solvent

In vitro
Batch:

Water : 100 mg/mL

DMSO : Insoluble ( Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Ethanol : Insoluble

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In vivo
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Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

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