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Check the
LY2835219 (Abemaciclib) Mesylate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| DMSO |
24 mg/mL
(39.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | 100 mg/mL |
| DMSO |
83 mg/mL
(137.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 24 mg/mL |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
33 mg/mL
(54.75 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| DMSO |
50 mg/mL
(82.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | 100 mg/mL |
| DMSO |
33 mg/mL
(54.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
| Form | Storage Temp | Shelf Life |
|---|---|---|
| Powder | -20°C | 3 years |
| In Solvent | -80°C | 1 year |
| In Solvent | -20°C | 1 month |
Search directly for a cell line, or select a cell line to find matched working concentrations
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- LY2835219 (Abemaciclib) Mesylate Mechanism of Action: CDK4/6 Inhibition in Breast Cancer Cell Research
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- LY2835219 (Abemaciclib) Mesylate Working Concentration | Cell Culture | Treatment
- LY2835219 (Abemaciclib) Mesylate Solubility in DMSO
- LY2835219 (Abemaciclib) Mesylate Storage
- LY2835219 (Abemaciclib) Mesylate Stability
- LY2835219 (Abemaciclib) Mesylate Combination Database
- LY2835219 (Abemaciclib) Mesylate Molecular Weight
- LY2835219 (Abemaciclib) Mesylate SMILES
- LY2835219 (Abemaciclib) Mesylate CAS Number
- LY2835219 (Abemaciclib) Mesylate Chemical Structure (2D and 3D)
- LY2835219 (Abemaciclib) Mesylate IC50 for Cell-based and Cell-free Assays
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- LY2835219 (Abemaciclib) Mesylate SDS|MSDS
Note: Technical data last updated: Sep 1, 2026.