2D Structure
loading...
2D chemical structural formula diagram.
3D Structure
loading...
This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
LY2835219 (Abemaciclib) Mesylate
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | N-[5-[(4-ethylpiperazin-1-yl)methyl]-2-pyridinyl]-5-fluoro-4-(7-fluoro-2-methyl-3-propan-2-ylbenzimidazol-5-yl)pyrimidin-2-amine;methanesulfonic acid | |
|---|---|---|
| CAS Number | 1231930-82-7 | |
| Molecular Formula |
C27H32F2N8.CH4O3S |
|
| Molecular Weight (MW) | 602.7 | |
| SMILES | CCN1CCN(CC1)CC2=CN=C(C=C2)NC3=NC=C(C(=N3)C4=CC5=C(C(=C4)F)N=C(N5C(C)C)C)F.CS(=O)(=O)O | |
| InChIKey | NCJPFQPEVDHJAZ-UHFFFAOYSA-N |
|
Concentration
Volume
Mass
|
1 mg | 5 mg | 10 mg |
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| Water | 100 mg/mL |
| DMSO |
24 mg/mL
(39.82 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | 100 mg/mL |
| DMSO |
83 mg/mL
(137.71 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 24 mg/mL |
| Water | 100 mg/mL |
| Ethanol | 100 mg/mL |
| DMSO |
33 mg/mL
(54.75 mM)
; Warmed with 60°C water bath
; Ultrasonicated
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | 100 mg/mL |
| DMSO |
50 mg/mL
(82.96 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 13 mg/mL |
| Water | 100 mg/mL |
| DMSO |
33 mg/mL
(54.75 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 4 mg/mL |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- LY2835219 (Abemaciclib) Mesylate Mechanism of Action: CDK4/6 Inhibition in Breast Cancer Cell Research
- LY2835219 (Abemaciclib) Mesylate Clinical Trials
- LY2835219 (Abemaciclib) Mesylate: Selectivity & Specificity
- LY2835219 (Abemaciclib) Mesylate Working Concentration | Cell Culture | Treatment
- LY2835219 (Abemaciclib) Mesylate Solubility in DMSO
- LY2835219 (Abemaciclib) Mesylate Stock Solution
- LY2835219 (Abemaciclib) Mesylate Storage
- LY2835219 (Abemaciclib) Mesylate Stability
- LY2835219 (Abemaciclib) Mesylate Combination Database
- LY2835219 (Abemaciclib) Mesylate Molecular Weight
- LY2835219 (Abemaciclib) Mesylate SMILES
- LY2835219 (Abemaciclib) Mesylate CAS Number
- LY2835219 (Abemaciclib) Mesylate IC50 for Cell-based and Cell-free Assays
- LY2835219 (Abemaciclib) Mesylate Cayman (17740)? Try a better option.
- LY2835219 (Abemaciclib) Mesylate MedChemExpress (HY-16297)? Try a better option.
- LY2835219 (Abemaciclib) Mesylate Sigma (AMBH2D6FA628)? Try a better option.
- LY2835219 (Abemaciclib) Mesylate SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.