| Cat.No. | Product Name | Information |
|---|---|---|
| E0205 | Strictosamide | Strictosamide is the main representative constituent of Nauclea officinalis Pierre ex Pitard (Rubiaceae) with anti-inflammatory and analgesic activities. |
| S7758 | Trabectedin | Trabectedin (Ecteinascidin 743, ET-743) is a marine alkaloid isolated from the Caribbean tunicate Ecteinascidia turbinata with antitumour activity. Trabectedin binds to the N2 of guanine in the minor groove, causing DNA damage and affecting transcription regulation in a promoter- and gene-specific manner. |
| S0651 | N-Butanoyl-L-homoserine lactone | N-Butyryl-L-homoserine lactone (N-Butanoyl-L-homoserine lactone, N-Butyrylhomoserine lactone, C4-HSL) is a cleavable ADC linker applied into the synthesis of antibody-drug conjugates (ADCs). N-Butyryl-L-homoserine lactone is a small diffusible signaling molecule involved in quorum sensing, controlling gene expression, and cellular metabolism. |
| E0160 | Hexaminolevulinate hydrochloride |
Hexaminolevulinate hydrochloride (5-Aminolevulinic acid hexyl ester hydrochloride) is a tumour photosensitizer. |
| E0365 | Fucoidan |
Fucoidan is an anionic sulfated polysaccharide extracted from marine brown algae with a large range of biological activities, including anti-inflammatory, anti-cancer, anti-viral, anti-oxidation, anticoagulant, antithrombotic, anti-angiogenic and anti-Helicobacter pylori, etc. |
| S0920 | Ginkgolide J | Ginkgolide J is a minor constituent of terpene trilactone mixture of Ginkgo biloba leaves extract that inhibits GlyR-operated channels with IC50 of 2.0 μM. This compound also inhibits cell death of rodent hippocampal neurons caused by Aβ1–42. It exhibits anti‑inflammatory activity. |
| E0198 | Pristane |
Pristane (2,6,10,14-Tetramethylpentadecane, TMPD) is a natural saturated terpenoid alkane obtained primarily from shark liver oil that is widely used to induce tumorgenesis in mice and arthritis and lupus nephritis in rats. This compound can be used to induce animal models of Systemic Lupus Erythematosus. |
| E1029 | Miglustat |
Miglustat (Zavesca, N‐butyldeoxynojirimycin, OGT 918) is an orally administered ceramide glucosyltransferase inhibitor which prevents the lysosomal accumulation of glucocerebroside. |
| E0196 | Alloxan Monohydrate |
Alloxan Monohydrate is the most popular diabetogenic agents used for assessing the antidiabetic or hypoglycemic capacity of test compounds. Alloxan Monohydrate can be used to induce animal models of Diabetes Mellitus. |
| S9793 | 4-HNE (4-Hydroxynonenal) | 4-HNE (4-Hydroxynonenal) is one of the major end products of lipid peroxidation and has been widely accepted as an inducer of oxidative stress. |
| E0150 | Carrageenan |
Carrageenan (kappa-Carrageenan) is a natural carbohydrate (polysaccharide) obtained from edible red seaweeds. This compound shows anticoagulant activity, antithrombotic activity, antiviral activity, anti-tumour activity and immunomodulatory activity. It can be used to induce animal models of Prostatitis. |
| E0149 | Papain |
Papain (papaya proteinase I) is a sulfhydryl protease from the latex of the papaya fruit. This enzyme breaks down intercellular matrix of cartilage. This compound can be used to induce animal models of Emphysema. |
| E0156 | Thioacetamide |
Thioacetamide (TAA) is a hepatotoxin frequently used for experimental purposes which produces centrilobular necrosis after a single dose administration. This compound can be used to induce animal models of Cirrhosis. |
| E0154 | Taurocholic acid sodium salt |
Taurocholic acid sodium salt (Sodium Taurocholate, TANa) is a sodium salt of taurocholic acid and occurs in the bile of mammals. Taurocholic acid is used as a cholagogue and choleretic. |
| E0143 | ITE |
ITE (2-(1′H-indole-3′-carbonyl)-thiazole-4-carboxylic acid methyl ester) is a potent endogenous agonist of aryl hydrocarbon receptor (AhR) that directly binds to AHR with a Ki of 3 nM. |
| S6812 | Z-Guggulsterone | Z-Guggulsterone, a constituent of Ayurvedic medicinal plant Commiphora mukul, inhibits angiogenesis in vitro and in vivo. This compound exhibits anti-inflammatory effects in microglia. It induces apoptosis in gastric cancer cells through the intrinsic mitochondria-dependent pathway. |
| E0129 | Oxysophocarpine | Oxysophocarpine (OSC) is an alkaloid extracted from Sophora alopecuroides. This compound inhibits the growth and metastasis of oral squamous cell carcinoma (OSCC) by targeting the Nrf2/HO-1 axis. It protects cells against apoptosis and inflammatory responses and compromised miR-155 activity by attenuating MAPK and NF-κB pathways. |
| E0130 | Apigenin-7-O-glucuronide |
Apigenin-7-O-glucuronide (Apigenin-7-glucuronide) is the major flavonoid found in milk thistle. Apigenin 7-o-glucuronide inhibits tumor necrosis factor alpha (TNF-α) and total nitrite release in lipopolysaccharide-activated macrophages. |
| S0947 | Cafestol | Cafestol is a natural diterpenes extracted from coffee beans. It induces apoptosis and regulates a variety of inflammatory mediators to reduce inflammation. This compound inhibits the PI3K/Akt pathway and can also reduce the production of ROS in the leukemia cell line HL60. |
| E0066 | Theaflavin 3,3'-digallate | Theaflavin 3,3'-digallate (TF-3, ZP10, TFDG) is a black tea polyphenol and acts as a potent Zika virus (ZIKV) protease inhibitor with an IC50 of 2.3 μM. |