GNRH Receptor
Inhibitory Selectivity
GNRH Receptor Products
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S5808 |
RelugolixRelugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively. |
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S4896 |
Elagolix SodiumElagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%). |
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P1089 |
Goserelin AcetateGoserelin is a luteinizing hormone releasing hormone (LHRH) agonist, which is used to suppress production of the sex hormones. Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist). |
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S3718 |
Leuprolide AcetateLeuprolide acetate (Leuprorelin) is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
S5808 |
RelugolixRelugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively. |
||
S4896 |
Elagolix SodiumElagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%). |
Catalog No. | Information | Product Use Citations | Product Validations |
---|---|---|---|
P1089 |
Goserelin AcetateGoserelin is a luteinizing hormone releasing hormone (LHRH) agonist, which is used to suppress production of the sex hormones. Goserelin acetate is an injectable gonadotropin releasing hormone superagonist (GnRH agonist). |
||
S3718 |
Leuprolide AcetateLeuprolide acetate (Leuprorelin) is a synthetic nonapeptide that is a potent gonadotropin-releasing hormone receptor (GnRHR) agonist used for diverse clinical applications, including the treatment of prostate cancer, endometriosis, uterine fibroids, central precocious puberty and in vitro fertilization techniques. |