GNRH Receptor

Other GPCR & G Protein Related Inhibitors

Hedgehog/Smoothened PKA CGRP Receptor Endothelin Receptor S1P Receptor Cannabinoid Receptor SGLT Opioid Receptor GPR CCR

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S5808	Relugolix (TAK-385, RVT-601)	Relugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively.	iScience, 2024, 27(10):110862
S4896	Elagolix Sodium	Elagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).	iScience, 2023, 26(5):106749 J Int Med Res, 2022, 50(3):3000605221082895 Nat Commun, 2020, 11(1):5287

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S5808

Relugolix (TAK-385, RVT-601)

Relugolix (RVT-601, TAK-385) is a selective antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with IC50 of 0.33 nM and 0.32 nM for human GnRHR and monkey GnRHR, respectively.

iScience, 2024, 27(10):110862

S4896

Elagolix Sodium

Elagolix Soidum (NBI-56418, ABT-620) is a potent, selective, orally active, non-peptide antagonist of the gonadotropin-releasing hormone receptor (GnRHR) with Kd value of 54 pM. Concentration at 10 μM shows no significant activity on ion channels, enzymes, and transporters (inhibition <50%).

iScience, 2023, 26(5):106749

J Int Med Res, 2022, 50(3):3000605221082895

Nat Commun, 2020, 11(1):5287