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Degarelix

Cat.No.P1284

Degarelix (FE 200486 free base) is a water-soluble GnRH antagonist with an IC50 of 3 nM. It exhibits profound and sustained suppression of testosterone in patients with prostate cancer.

Amino-acid Sequence

CAS No. 214766-78-6

Quality Control

Batch: P128401 DMSO] 100 mg/mL] false] Water] 100 mg/mL] false] Ethanol] Insoluble] false Purity: 99.38%

99.38

Featured Inhibitors	Y-27632 Dihydrochloride SB431542 CHIR-99021 (Laduviglusib) RMC-7977 RMC-6236 (Daraxonrasib) MRTX1133 MG132 Z-VAD-FMK VT3989 IAG933

Chemical Information & Solubility

Storage (From the date of receipt)	3 years-20°Cpowder	Storage of Stock Solutions Aliquot the stock solutions to avoid repeated freeze-thaw cycles	1 year-80°Cin solvent
			1 month-20°Cin solvent

In vitro
Batch:

DMSO : 100 mg/mL (61.26 mM)；
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO.)

Water : 100 mg/mL

Ethanol : Insoluble

Molecular Weight Calculator

In vivo
Batch:

Add solvents to the product individually and in order.

In vivo Formulation Calculator

Biological Activity

Description	Degarelix (FE 200486 free base) is a water-soluble GnRH antagonist with an IC50 of 3 nM. It exhibits profound and sustained suppression of testosterone in patients with prostate cancer.

References
https://pubmed.ncbi.nlm.nih.gov/17179469/

References

https://pubmed.ncbi.nlm.nih.gov/17179469/

Product Information

Molecular Formula	C₈₂H₁₀₃ClN₁₈O₁₆
Molecular Weight	1632.26
CAS No.	214766-78-6
Shipping	Room temperature shipping(Stability testing shows this product can be shipped without any cooling measures.)