ER stress

Other ER stress & UPR Related Inhibitors

PERK IRE1 PDI PKR ATF-6

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S7894	Tunicamycin	Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.	Proc Natl Acad Sci U S A, 2025, 122(22):e2505975122 Cell Rep, 2025, 44(5):115686 Eur Endod J, 2024, 9(4):335-343
S3654	Tauroursodeoxycholic Acid (TUDCA)	Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).	Nat Commun, 2025, 16(1):50 Toxicol Appl Pharmacol, 2025, 499:117333 Cell Mol Life Sci, 2024, 81(1):299

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S7894

Tunicamycin

Tunicamycin, an antibiotic, can potently inhibit the N-linked glycosylation (NLG) by competitively inhibiting UDP-GlcNAc-dolichol-phosphate N-acetylglucosamine-1 phosphate transferase (DPAGT1) activity and can target several types of tumors by reducing angiogenesis, inhibiting colony formation, and enhancing TRAIL-induced apoptosis.

Proc Natl Acad Sci U S A, 2025, 122(22):e2505975122

Cell Rep, 2025, 44(5):115686

Eur Endod J, 2024, 9(4):335-343

S3654

Tauroursodeoxycholic Acid (TUDCA)

Tauroursodeoxycholic acid (TUDCA) is the taurine conjugate of ursodeoxycholic acid (UDCA) and acts as a mitochondrial stabilizer and anti-apoptotic agent in several models of neurodegenerative diseases, including AD, Parkinson's diseases (PD), and Huntington's diseases (HD).

Nat Commun, 2025, 16(1):50

Toxicol Appl Pharmacol, 2025, 499:117333

Cell Mol Life Sci, 2024, 81(1):299