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CD markers Antagonists

Cat.No. Product Name Information Product Use Citations Product Validations
S6239 PMX-53 PMX-53 is a potent CD88 (C5aR) antagonist and inhibits C5a-induced neutrophil myeloperoxidase release and chemotaxis with IC50 values of 22 nM and 75 nM, respectively. This compound is also an agonist of Mas-related gene 2 (MrgX2).
Redox Biol, 2025, 86:103802
Biomolecules, 2025, 15(8)1106
Thromb J, 2022, 20(1):24
S0474 Avacopan (CCX168) Avacopan is an orally administered and selective C5a receptor (C5aR) antagonist.
Br J Cancer, 2025, 10.1038/s41416-025-03185-0
Nat Commun, 2024, 15(1):6519
Cell Death Dis, 2022, 13(5):500
P1208 PMX 205 acetate

PMX 205 acetate is a cyclic hexapeptide that acts as a potent C5a receptor (C5aR, CD88) antagonist with an IC50 of 31 nM.
Ecotoxicol Environ Saf, 2025, 289:117627
Int Immunopharmacol, 2023, 125(Pt B):111112