TNF-alpha Modulators

Cat.No. Product Name Information Product Use Citations Product Validations
E3024 Ampelopsis Japonica Root Extract Ampelopsis Japonica Root Extract is extracted from Ampelopsis japonica, may be a new therapeutic agent with the potential to reduce or replace corticosteroids and its mechanisms are closely related to regulation of TNF-α production.
S1537 Vadimezan (DMXAA) Vadimezan (DMXAA) is a vascular disrupting agents (VDA) and competitive inhibitor of DT-diaphorase with Ki of 20 μM and IC50 of 62.5 μM in cell-free assays, respectively. It is also a STING agonist with potential antineoplastic activity, potently inducing IFN-β but relatively low TNF-α expression in vitro. This compound has antiviral activity. Phase 3.
Cell Chem Biol, 2025, 32(2):280-290.e14
Commun Biol, 2025, 8(1):1470
Front Pharmacol, 2025, 16:1528459
Verified customer review of Vadimezan (DMXAA)
E3633 Ginger Extract Ginger Extract is extracted from Zingiber officinale Roscoe, which has antioxidant potential and regulates STAT6 and TNF- α pathways.
E3634 Ginger Extract(1%) Ginger Extract(1%) is extracted from Zingiber officinale Roscoe, which has antioxidant potential and regulates STAT6 and TNF- α pathways.