TNF-alpha Antagonists

Featured Inhibitors
Inhibitors (55)
Modulators (4)
Agonists (3)
Activators (4)
Antagonists (2)

Cat.No.	Product Name	Information	Product Use Citations	Product Validations
S6643	R-7050	R-7050 is a cell permeable TNF-α receptor antagonist and is 2.3-fold more selective for TNF-α-mediated signaling than for that driven by IL-1β.	Int Immunopharmacol, 2024, 143(Pt 2):113521 Ren Fail, 2023, 45(1):2220418 Elife, 2022, 11e73792
S5851	4'-Methoxychalcone	4'-Methoxychalcone, found in citrus, is chalcone derivative that has shown diverse pharmacological properties, including anti-tumor and anti-inflammatory activities. This compound significantly enhanced adipocyte differentiation, in part, by its potent effects on PPARγ activation and by its reverse effect on TNF-α.

Cat.No.

Product Name

Information

Product Use Citations

Product Validations

S6643

R-7050

R-7050 is a cell permeable TNF-α receptor antagonist and is 2.3-fold more selective for TNF-α-mediated signaling than for that driven by IL-1β.

Int Immunopharmacol, 2024, 143(Pt 2):113521

Ren Fail, 2023, 45(1):2220418

Elife, 2022, 11e73792

S5851

4'-Methoxychalcone

4'-Methoxychalcone, found in citrus, is chalcone derivative that has shown diverse pharmacological properties, including anti-tumor and anti-inflammatory activities. This compound significantly enhanced adipocyte differentiation, in part, by its potent effects on PPARγ activation and by its reverse effect on TNF-α.