Opioid Receptor Agonists

Cat.No.	Product Name	Information	Product Use Citations
S2480	Loperamide HCl	Loperamide HCl (ADL 2-1294,R-18553 hydrochloride) is a selective μ-opioid receptor agonist opioid with K_i of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or inflammatory bowel disease.	Cancer Cell, 2025, 43(4):776-796.e14 Front Neurosci, 2024, 18:1424936 Front Cell Infect Microbiol, 2023, 13:1139152
S2322	(+)-Matrine	Matrine((+)-Matrine) is an alkaloid found in plants from the Sophora family, which has a variety of pharmacological effects, including anti-cancer effects, and action as a kappa opioid receptor agonist.	Frontiers in Pharmacology, October 21, 2022, 1027441 Journal for ImmunoTherapy of Cancer, June 26, 2025, e011716 J Immunother Cancer, 2025, 13(6)e011716
S0009	Asimadoline hydrochloride	Asimadoline hydrochloride (EMD-61753 hydrochloride) is an orally active, selective and peripherally active κ-opioid agonist with IC50s of 5.6 nM (guinea pig) and 1.2 nM (human recombinant).
S5507	Trimebutine maleate	Trimebutine maleate is the maleate salt form of trimebutine, which is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu opioid agonist effects.
E7164	β-Endorphin, human	β‑Endorphin, human is a prominent endogenous peptide of the hypothalamus and hypophysis cerebri that acts as an agonist of opioid receptors, with preferred affinity for μ‑opioid receptors and δ‑opioid receptors, and exhibits antinociceptive activity.
S2085	Trimebutine	Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.