Opioid Receptor Inhibitors

Cat.No.	Product Name	Information
E2868	Naloxegol Oxalate	Naloxegol oxalate (NKTR-118 oxalate) is a μ-opioid-receptor antagonist with a Ki of 33.8 nM. Naloxegol oxalate inhibits opioid binding in μ-opioid receptors in the gastrointestinal tract and effective for alleviating opioid-induced constipation.
S4588	Docusate Sodium	Docusate Sodium (Aerosol OT, Bis(2-ethylhexyl) sulfosuccinate sodium salt, Constonate) is a laxative used to treat constipation, for constipation due to the use of opiates it maybe used with a stimulant laxative, can be taken by mouth or rectally.
E2880	methylnaltrexone bromide	Methylnaltrexone bromide is an antagonist of µ-opioid receptor that reduces the viability of lung cancer cells by inhibiting Src activation.
E7162	CTAP	CTAP is a potent, highly selective, and blood–brain barrier penetrant antagonist of μ opioid receptor with an IC50 of 3.5 nM. It displays over 1200-fold selectivity over δ opioid and somatostatin receptors. It exhibits anti-dyskinetic potential and can be used for the study of L-DOPA-induced dyskinesia (LID) and opiate overdose or addiction.
S2085	Trimebutine	Trimebutine (Mebutin) is an agonist of peripheral mu, kappa and delta opiate receptors, used as spasmolytic agent for treatment of both acute and chronic abdominal pain.