Research Area
Product Type
United States ( Change Country )
Bergenin (Cuscutin) Chemical Structure
[Ala92]-p16 (84-103)
[Ala92]-p16 (84-103) is a CDK inhibitor with IC50 of 1.5μM for cyclin-dependent kinase-4 (cdk4)/cyclin D1
Bax inhibitor peptide,negative control
Bax inhibitor peptide,negative control is a negative control peptide for the Bax inhibitor peptides V5 and P5.
JIP-1(153-163)
JNK and p38 MAPK inhibitor
pp60 c-src (521-533)(phosphorylated)
SRC kinase inhibitor
STF-62247
Targeting VHL-deficient RCC cells, in renal cell carcinoma (RCC) cells that have lost the von Hippel-Lindau (VHL) tumor suppressor activity (IC50 = 625 μM).
BTZ043 racemate
BTZ043 racemate is a decaprenylphosphoryl-b-D-ribose 2’-epimerase inhibitor with MIC of 2.3 and 9.2 nM for M. tuberculosis H37Rv and Mycobacterium smegmatis, respectively.
GSK690693
GSK690693 is a pan-Akt kinase inhibitor,IC50 of Akt 1, 2, and 3 at 2, 13, and 9 nM respectively.
Odanacatib (MK 0822)
cathepsin K inhibitor with an IC50 of 0.2nM.
Malotilate
Malotilate is a liver protein metabolism improved compound.
PA-824
PA-824 is an experimental anti-tuberculosis drug with MIC of less than 1 μg/mL for tuberculosis.
Biological Activity
Bergenin (Cuscutin) is trihydroxybenzoic acid glycoside and the C-glycoside of 4-O-methyl gallic acid. It shows a potent immunomodulatory effect. It possesses an O-demethylated derivative called norbergenin. It can be isolated from Bergenia species like Bergenia ciliata and Bergenia ligulata and from rhizomes of Bergenia stracheyi. It is also found in Ardisia elliptica. [1]
Product Information
| Molecular Weight (WM): | 328.27 |
|---|---|
| Formula: | C14H16O9 |
| CAS No.: | 477-90-7 |
| Synonyms: |
Cuscutin
|
| Dissolve in (25°C): | DMSO ≥66mg/mL |
| Water <1mg/mL | |
| Ethanol <1mg/mL | |
| Storage: | 2 years-20°CPowder |
| 1 week-4°Cin DMSO | |
| 1 month-80°in DMSO |
Quality Control & MSDS
Research Area
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