CDK Modulator

Cat.No. Product Name Information Product Use Citations Product Validations
S7981 CCT251545 CCT251545 is a potent, orally bioavailable inhibitor of WNT signaling with IC50 of 5 nM in 7dF3 cells. This compound also acts as a selective chemical probe for exploring the role of CDK8 and CDK19 in human disease.
Science, 2022, 378(6620):eabn5647
Pathol Oncol Res, 2022, 28:1610273
Front Cell Dev Biol, 2020, 8:408