| S9794 |
Melittin
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Melittin (MLT, Forapin, Forapine) is an activator of phospholipase A2 (PLA2) that stimulates the activity of the low molecular weight PLA2, while it does not the increase the activity of the high molecular weight enzyme.
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Molecular Medicine Reports, October 18, 2024, 5
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Cell Death and Disease, August 8, 2024, 573
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Cell Death & Disease, August 08, 2024, 573
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| S0982 |
m-3M3FBS
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m-3M3FBS is a potent activator of phospholipase C (PLC) that stimulates a transient intracellular calcium concentration increase in neutrophils. This compound induces apoptosis in monocytic leukemia cells.
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The Journal of Clinical Investigation, 2025, e184522
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Pharmaceuticals (Basel), 2022, 15(12)1444
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Pharmaceuticals, 2022, 1444
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| S4107 |
Clofazimine
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Clofazimine (NSC-141046) is a rhimophenazine dye, originally developed for the treatment of tuberculosis, it has both antimicrobial and antiinflammatory activity, postulated mechanisms of action of this compound include intercalation of this chemical with bacterial DNA and increasing levels of cellular phospholipase A2.
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Viruses, 2024, 16(4)640
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Cell Rep Methods, 2023, 3(10):100599
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Blood, 2022, blood.2021014304
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