2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Lonafarnib (SCH66336)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
| IUPAC Name | 4-[2-[4-[(2R)-6,15-dibromo-13-chloro-4-azatricyclo[9.4.0.03,8]pentadeca-1(11),3(8),4,6,12,14-hexaen-2-yl]piperidin-1-yl]-2-oxoethyl]piperidine-1-carboxamide | |
|---|---|---|
| CAS Number | 193275-84-2 | |
| Molecular Formula |
C27H31Br2ClN4O2 |
|
| Molecular Weight (MW) | 638.82 | |
| SMILES | C1CN(CCC1CC(=O)N2CCC(CC2)C3C4=C(CCC5=C3N=CC(=C5)Br)C=C(C=C4Br)Cl)C(=O)N | |
| InChIKey | DHMTURDWPRKSOA-RUZDIDTESA-N |
|
Concentration
Volume
Mass
|
|---|
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
127 mg/mL
(198.8 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 127 mg/mL |
| Water | Insoluble |
| DMSO |
11 mg/mL
(17.21 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Water | Insoluble |
| Ethanol | Insoluble |
| DMSO |
100 mg/mL
(156.53 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 2 mg/mL |
| Water | Insoluble |
| DMSO |
40 mg/mL
(62.61 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 5 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer significantly longer shelf life compared to stock solutions, ensuring maximum stability for every use.
Looking for a specific aliquot size? Reach out to your local sales representative or contact us at orders@selleckchem.com.
- Lonafarnib (SCH66336) Mechanism of Action: Farnesyltransferase Inhibition in Fibroblast Research
- Lonafarnib (SCH66336) Clinical Trials
- Lonafarnib (SCH66336): Selectivity & Specificity
- Lonafarnib (SCH66336) Working Concentration | Cell Culture | Treatment
- Lonafarnib (SCH66336) Solubility in DMSO
- Lonafarnib (SCH66336) Stock Solution
- Lonafarnib (SCH66336) Storage
- Lonafarnib (SCH66336) Stability
- Lonafarnib (SCH66336) Combination Database
- Lonafarnib (SCH66336) Molecular Weight
- Lonafarnib (SCH66336) SMILES
- Lonafarnib (SCH66336) CAS Number
- Lonafarnib (SCH66336) IC50 for Cell-based and Cell-free Assays
- Lonafarnib (SCH66336) MedChemExpress (HY-15136)? Try a better option.
- Lonafarnib (SCH66336) Sigma (SML1457)? Try a better option.
- Lonafarnib (SCH66336) APExBIO (A4379)? Try a better option.
- Lonafarnib (SCH66336) Cayman (11746)? Try a better option.
- Lonafarnib (SCH66336) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.