Darapladib (SB-480848) IC50 for Cell-based and Cell-free Assays

Cell-free Assays (IC₅₀/K_i) for Darapladib (SB-480848)

Key Target	IC₅₀ (Cell-free)	Description	Reference
Lp-PLA2 enzyme in serum	< 50 nM	Lp-PLA2 activity inhibition assay; dose-response curve fitting	Download PDF

Cell-based Assay (IC₅₀) for Darapladib (SB-480848)

Cell Type	IC₅₀ (Cell-based)	Description	Reference
lipoprotein-associated phospholipase A2	subnanomolar	Enzyme assay	PMC12687644
DB cells	5.33 μM	CCK8 assay	Download PDF
SU-DHL-2 cells	12.92 μM	CCK8 assay	Download PDF
Candida albicans ATCC 10231	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida albicans BCPF 3153A	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida auris NCPF 8978	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida glabrata ATCC 2001	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida tropicalis BC064	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida haemulonii DSM 70624	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida parapsilosis NCPF 8334	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida krusei NCPF 3953	4 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida albicans SC5314	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida albicans ATCC 10231	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida albicans NCPF 3153A	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida auris NCPF 8973	64 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida auris NCPF 8978	64 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida glabrata ATCC 2001	8 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida tropicalis BC064	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida haemulonii DSM 70624	64 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida parapsilosis NCPF 8334	16 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida krusei NCPF 3953	32 lg/mL	XTT metabolic reduction assay	PMC9541805
Candida albicans BC023	8 lg/mL	Checkerboard microtiter assay, visual examination for PMIC	PMC9541805
Candida albicans BC146	0.5-8 lg/mL	Checkerboard microtiter assay, visual examination for PMIC	PMC9541805

Check the Darapladib (SB-480848) product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Size	Price	Qty
5mg	USD 147
25mg	USD 470
100mg	USD 970

Cell-free Assays (IC50/Ki) for Darapladib (SB-480848)

Cell-based Assay (IC50) for Darapladib (SB-480848)

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Cell-free Assays (IC₅₀/K_i) for Darapladib (SB-480848)

Cell-based Assay (IC₅₀) for Darapladib (SB-480848)