2D Structure
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2D chemical structural formula diagram.
3D Structure
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This 3D model represents a theoretically simulated conformation and is for reference only.
Check the
Darapladib (SB-480848)
product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.
Chemical Information
| IUPAC Name | N-[2-(diethylamino)ethyl]-2-[2-[(4-fluorophenyl)methylsulfanyl]-4-oxo-6,7-dihydro-5H-cyclopenta[d]pyrimidin-1-yl]-N-[[4-[4-(trifluoromethyl)phenyl]phenyl]methyl]acetamide | |
|---|---|---|
| CAS Number | 356057-34-6 | |
| Molecular Formula |
C36H38F4N4O2S |
|
| Molecular Weight (MW) | 666.77 | |
| SMILES | CCN(CC)CCN(CC1=CC=C(C=C1)C2=CC=C(C=C2)C(F)(F)F)C(=O)CN3C4=C(CCC4)C(=O)N=C3SCC5=CC=C(C=C5)F | |
| InChIKey | WDPFJWLDPVQCAJ-UHFFFAOYSA-N |
How to Prepare Stock Solution?
|
Concentration
Volume
Mass
|
|---|
Solubility
Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
| Solvent | Solubility & Note |
|---|---|
| DMSO |
100 mg/mL
(149.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(149.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 23 mg/mL |
| Water | Insoluble |
| DMSO |
100 mg/mL
(149.97 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.) |
| Ethanol | 100 mg/mL |
| Water | Insoluble |
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
- Preheat media/saline to 37°C.
- Mix rapidly (pipette/vortex) upon addition.
- For complex mixes, always add the aqueous phase last.
- Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).
Pre-aliquoted for Longevity: Solid-state aliquots offer longer shelf life compared to stock solutions.
Looking for a specific aliquot size? Contact your local sales representative or orders@selleckchem.com.
Jump to
- Darapladib (SB-480848) Mechanism of Action: Lp-PLA2 Inhibition in Cancer Cell Research
- Darapladib (SB-480848) Clinical Trials
- Darapladib (SB-480848) Working Concentration | Cell Culture | Treatment
- Darapladib (SB-480848) Solubility in DMSO
- Darapladib (SB-480848) Stock Solution
- Darapladib (SB-480848) Storage
- Darapladib (SB-480848) Stability
- Darapladib (SB-480848) Combination Database
- Darapladib (SB-480848) Molecular Weight
- Darapladib (SB-480848) SMILES
- Darapladib (SB-480848) CAS Number
- Darapladib (SB-480848) IC50 for Cell-based and Cell-free Assays
- Darapladib (SB-480848) APExBIO (A3349)? Try a better option.
- Darapladib (SB-480848) Sigma (SML3097)? Try a better option.
- Darapladib (SB-480848) Cayman (16429)? Try a better option.
- Darapladib (SB-480848) MedChemExpress (HY-10521)? Try a better option.
- Darapladib (SB-480848) SDS｜MSDS
Note: Technical data last updated: Sep 1, 2026.