Dapagliflozin (BMS-512148) Mechanism of Action: SGLT2 Inhibition in Renal Proximal Tubule Epithelial Cells Research

Dapagliflozin (BMS-512148) MOA:Targeting SGLT2/NHE1 for Heart Failure

🎯 check Dapagliflozin (BMS-512148) product page

Dapagliflozin (BMS-512148) is a highly potent, selective, and reversible SGLT2 inhibitor. It affects AMPK, PI3K/AKT, and NF-κB signaling pathways by blocking sodium-glucose co-transport and reducing oxidative stress, effectively inhibiting inflammation, apoptosis, and fibrosis.

Primary Applications and Mechanism of Action