Dapagliflozin (BMS-512148) is a highly potent, selective, and reversible SGLT2 inhibitor. It affects AMPK, PI3K/AKT, and NF-κB signaling pathways by blocking sodium-glucose co-transport and reducing oxidative stress, effectively inhibiting inflammation, apoptosis, and fibrosis.
Dapagliflozin (BMS-512148) IC50 for Cell-based and Cell-free Assays
Comprehensive IC50 Values for Dapagliflozin (BMS-512148) Across Cell-free Enzyme Inhibitory Profiles and Cell-based Functional Assays.