Target Selectivity of Adagrasib (MRTX849)
| Key Target | IC50 | Description | Reference |
|---|---|---|---|
| KRAS | 1000 nM | preclinical study using N-ethyl-N-nitrosourea (ENU) mutagenesis screens (KRASG12C/Y96D mutant Ba/F3 cells) | PMC9800313 |
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Adagrasib (MRTX849)
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- Adagrasib (MRTX849) Mechanism of Action: KRAS G12C Inhibition in Lung Adenocarcinoma Cell Research
- Adagrasib (MRTX849) Clinical Trials
- Adagrasib (MRTX849) Working Concentration | Cell Culture | Treatment
- Adagrasib (MRTX849) Solubility in DMSO
- Adagrasib (MRTX849) Stock Solution
- Adagrasib (MRTX849) Storage
- Adagrasib (MRTX849) Stability
- Adagrasib (MRTX849) Combination Database
- Adagrasib (MRTX849) Molecular Weight
- Adagrasib (MRTX849) SMILES
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- Adagrasib (MRTX849) Chemical Structure (2D and 3D)
- Adagrasib (MRTX849) IC50 for Cell-based and Cell-free Assays
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- Adagrasib (MRTX849) SDS｜MSDS