2-Aminoethanethiol

Synonyms: cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine

2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.

2-Aminoethanethiol Chemical Structure

2-Aminoethanethiol Chemical Structure

CAS: 60-23-1

Purity & Quality Control

Batch: Purity: 99.97%
99.97

2-Aminoethanethiol Related Products

Biological Activity

Description 2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.
NCT Number Recruitment Conditions Sponsor/Collaborators Start Date Phases
NCT03000348 Completed
Cystic Fibrosis
NovaBiotics Ltd.|Agility Clinical Inc.|PSR Group B.V.
December 2016 Phase 2
NCT02212431 Completed
Cystic Fibrosis
University of Aberdeen|Cystic Fibrosis Trust|NHS Grampian|University of Huddersfield
August 2014 Phase 1|Phase 2
NCT01733316 Completed
Cystinosis
Horizon Pharma USA Inc.
January 31 2013 Phase 3
NCT01744782 Completed
Cystinosis
Horizon Pharma USA Inc.
December 20 2012 Phase 3
NCT02012114 Completed
Cystinosis
Hospices Civils de Lyon
December 2011 Not Applicable

Chemical Information & Solubility

Molecular Weight 77.15 Formula

C2H7NS

CAS No. 60-23-1 SDF --
Smiles C(CS)N
Storage (From the date of receipt) 3 years -20°C powder

In vitro
Batch:

DMSO : 15 mg/mL ( (194.42 mM); Moisture-absorbing DMSO reduces solubility. Please use fresh DMSO.)

Water : 15 mg/mL

Ethanol : 15 mg/mL


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In vivo
Batch:

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In vivo Formulation Calculator

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In vivo Formulation Calculator (Clear solution)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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