2-Aminoethanethiol

Catalog No.S6402 Synonyms: cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Decarboxycysteine, Thioethanolamine, Mercaptamine

For research use only.

2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.

2-Aminoethanethiol Chemical Structure

CAS No. 60-23-1

Purity & Quality Control

Related Other Products

Biological Activity

Description 2-Aminoethanethiol (cysteamine, β-Mercaptoethylamine, 2-Mercaptoethylamine, Thioethanolamine, Mercaptamine) is a radiation-protective agent that oxidizes in air to form cystamine.

Protocol (from reference)

Solubility (25°C)

In vitro

DMSO 15 mg/mL
(194.42 mM)
Water 15 mg/mL
(194.42 mM)
Ethanol 15 mg/mL
(194.42 mM)

* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Chemical Information

Molecular Weight 77.15
Formula

C2H7NS

CAS No. 60-23-1
Storage 3 years -20°C powder
2 years -80°C in solvent
Smiles C(CS)N

In vivo Formulation Calculator (Clear solution)

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such
as vortex, ultrasound or hot water bath can be used to aid dissolving.

Molarity Calculator

Mass Concentration Volume Molecular Weight

Clinical Trial Information

NCT Number Recruitment Interventions Conditions Sponsor/Collaborators Start Date Phases
NCT03000348 Completed Drug: Cysteamine|Drug: Placebo Oral Capsule Cystic Fibrosis NovaBiotics Ltd.|Agility Clinical Inc.|PSR Group B.V. December 2016 Phase 2
NCT02212431 Completed Drug: Cysteamine Cystic Fibrosis University of Aberdeen|Cystic Fibrosis Trust|NHS Grampian|University of Huddersfield August 2014 Phase 1|Phase 2
NCT01733316 Completed Drug: RP103|Drug: Cystagon® Cystinosis Horizon Pharma USA Inc. January 31 2013 Phase 3
NCT01744782 Completed Drug: RP103 Cystinosis Horizon Pharma USA Inc. December 20 2012 Phase 3
NCT02012114 Unknown status Other: Cysteamine bitartrate Cystinosis Hospices Civils de Lyon December 2011 Not Applicable
NCT01432561 Completed Drug: Cysteamine bitartrate Cystinosis|Nephropathic Cystinosis University of California San Diego|Raptor Pharmaceuticals Corp. September 2011 Not Applicable

(data from https://clinicaltrials.gov, updated on 2022-01-17)

Tech Support

Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store inhibitors, and issues that need special attention for cell-based assays and animal experiments.

Handling Instructions

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