CAS No. 60-23-1

Batch: Purity:99.97
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2-Aminoethanethiol Chemical Structure
Chemical Structure
Check the 2-Aminoethanethiol product page for in-depth specifications, including solubility, stock solutions, MOA, and working concentrations.

Chemical Information

CAS Number 60-23-1
Molecular Formula

C2H7NS
Molecular Weight (MW) 77.15
SMILES C(CS)N

Ordering Information

Biological Activity

2-Aminoethanethiol (cysteamine) is an orally active aminothiol compound that acts as a radioprotective agent and transglutaminase inhibitor. It modulates oxidative stress pathways and reduces pathological protein cross-linking by inhibiting transglutaminase activity. In preclinical models of neurodegenerative conditions, such as Huntington's disease, 2-aminoethanethiol decreases abnormal protein aggregation, reduces brain atrophy, and prolongs survival. [1]

How to Prepare Stock Solution?

Concentration Volume Mass
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Solubility

Batch:
All in vitro solubility values are batch-tested experimental data (non-literature values).
Solvent Solubility & Note
DMSO 15 mg/mL (194.42 mM)
(Moisture-contaminated DMSO may reduce solubility. Use fresh, anhydrous DMSO. The recommended stock concentration is 10 mM in DMSO.)
Water 15 mg/mL
Ethanol 15 mg/mL
FAQ
Q: Why does a DMSO stock precipitate in media/saline?
A: It is caused by unheated aqueous media (supersaturation), local solvent shock, or incorrect mixing sequence.
How to fix it?
  • Preheat media/saline to 37°C.
  • Mix rapidly (pipette/vortex) upon addition.
  • For complex mixes, always add the aqueous phase last.
  • Re-dissolve minor precipitates with a 37°C water bath and sonication (≤30 min).

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Note: Technical data last updated: Sep 1, 2026.