Platelet aggregation

Other GPCR & G Protein Related Inhibitors

Hedgehog/Smoothened PKA CGRP Receptor Endothelin Receptor S1P Receptor Cannabinoid Receptor SGLT Opioid Receptor GPR CCR

Cat.No.	Product Name	Information	Product Use Citations
S4492	Dextran	Dextran (Dextran 40, Macrodex) is a kind of biocompatible, nontoxic and nonimmunogenic biological substance that has been widely used in drug-delivery systems.
S4495	Quinine	Quinine, an alkaloid derived from the bark of the cinchona tree, is an anti-malaria agent and a potassium channel inhibitor that inhibits mSlo3 (KCa 5.1) channel currents evoked by voltage pulses to +100 mV with IC50 of 169 μM.	Cell Mol Immunol, 2022, 19(8):925-943 J Pharmacol Toxicol Methods, 2017, 90:39-47
S0141	NQ301	NQ301 (Compound 211), an antiplatelet and antithrombotic agent, is a selective CD45 inhibitor with IC50 of 200 nM. This compound inhibits thromboxane A2 receptor (TXA2) and synthase activity in rabbit platelets.	J Extracell Vesicles, 2021, 10(5):e12078
S5271	Suloctidil	Suloctidil, a sulfur-containing aminoalcohol showing to inhibit human platelet aggregation, is a peripheral vasodilator and a potential antifungal agent.
S9360	4-Hydroxyquinazoline	4-Hydroxyquinazoline (Quinazolin-4-ol, 4-Quinazolinol) is a PARP inhibitor with a high potency for PARP-1 with IC50 of 9.5 μM.
S3711	Carbasalate Calcium	Carbasalate calcium (Iromin, Alcacyl, Omegin, Rheomin, Solupsan) is an analgesic, antipyretic, and anti-inflammatory drug as well as a platelet aggregation inhibitor.
S3883	Protopine	Protopine (Corydinine, Fumarine, Biflorine, Macleyine), an alkaloid present in different plants, has been shown to exhibit a number of activities, such as inhibition of calcium influx through both voltage and receptor-operated channels and inhibition of rabbit blood platelet aggregation. It also possesses anti-cholinergic and anti-histaminic as well as anti-bacterial activities.