Mitochondrial Metabolism Activator

Cat.No. Product Name Information Product Use Citations Product Validations
E5826New MASM7 MASM7 is an activator of mitofusins that promotes mitochondrial fusion through mitofusins. It increases mitochondrial AR in MEFs in a concentration-dependent manner, with an EC50 value of 75 nM. This compound also directly binds to the HR2 domain of MFN2 with a dissociation constant (Kd) of 1.1 μM, effectively activating MFN2 or MFN to induce fusion.
J Adv Res, 2025, S2090-1232(25)00955-5